CONSORT diagram. A total of 355 patients were previously randomly assigned to the parent trial, 39 of whom received no intervention and were excluded from the analysis. A total of 316 patients (N = 195 surgical and N = 121 medical/lifestyle) patients were evaluated for eligibility and participation in the ARMMS-T2D trial. A total of 60 patients (N = 24 surgical and N = 36 medical/lifestyle) patients were excluded from the analysis based on their missing HbA1c values for 3 years. A total of 256 patients (N = 171 surgical and N = 85 medical/lifestyle) patients were included in the analysis of primary and secondary outcomes. credit: diabetes care (2022). DOI: 10.2337/dc21-2441
Remission of type 2 diabetes is achieved more effectively and with longer lasting results with bariatric surgery than with medication or lifestyle changes.
New study from Pennington Biomedical Research Center published in journal diabetes care, evaluated 316 patients with type 2 diabetes to determine the efficacy and long-term outcome of metabolic surgery. This is the largest study to date to evaluate metabolic surgery, also known as bariatric surgery, as a treatment for type 2 diabetes.
According to the Centers for Disease Control and Prevention, more than 34.2 million Americans, or 10.5% of the population, have type 2 diabetes. Obesity is a major contributor to the development of diabetes. About 90% of people with type 2 diabetes are overweight or obese. These intertwined chronic health problems pose enormous health burdens at both individual and societal levels.
“Treatment guidelines by the American Medical Association, the American Diabetes Association, and many other major medical organizations state that metabolic surgery is an effective treatment for type 2 diabetes,” Study. “Despite a growing consensus, many health insurers do not offer coverage for metabolic surgery. This is because there have not been sufficiently large randomized controlled trials that take into account the
“Only 2.6% of patients achieved diabetes remission during the study, even though they were educated on nutrition, exercise, self-monitoring, and the latest diabetes drugs on the market,” said Dr. Kirwan. says. “When we looked at patients who underwent metabolic surgery, even after 3 years he was 37.5% achieving durable remission of diabetes,” he added.
The study noted that less than 1% of patients eligible for bariatric surgery received treatment. This is likely due to concerns of both patients and providers for long-term safety and durable outcomes.
The study also found that metabolic surgery was superior to medication and lifestyle changes in reducing HbA1c, fasting blood glucose, body weight, and other cardiovascular risk factors with significantly less medication. rice field.
“We hope that physicians will have greater confidence in recommending bariatric surgery to their patients and that health insurance companies will understand the health benefits and ultimately cost savings that can be achieved by covering metabolic surgery.” We are doing it,” said Dr. Kirwan.
Increased weight loss after bariatric surgery associated with diabetes remission
John P. Kirwan et al., Diabetes remission in an alliance of randomized clinical trials and metabolic surgery in type 2 diabetes (ARMMS-T2D), diabetes care (2022). DOI: 10.2337/dc21-2441
Courtesy of Pennington Biomedical Research Center
Quote: Bariatric Surgery More Effective than Lifestyle Changes in Remission of Type 2 Diabetes (September 1, 2022)
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